usb wireless mouse freeze periodically in ubuntu 12.04 lts, edit /boot/grub/grub.cfg, add a boot option irqpoll will fix it

menuentry 'Ubuntu, with Linux 3.8.0-41-generic' --class ubuntu --class gnu-linux --class gnu --class os {
	recordfail
	gfxmode $linux_gfx_mode
	insmod gzio
	insmod part_msdos
	insmod ext2
	set root='(hd0,msdos1)'
	search --no-floppy --fs-uuid --set=root 4abd314f-d625-417d-b9f1-52ae7df8d1fd
	linux	/boot/vmlinuz-3.8.0-41-generic root=UUID=4abd314f-d625-417d-b9f1-52ae7df8d1fd ro   quiet splash nomodeset $vt_handoff irqpoll
	initrd	/boot/initrd.img-3.8.0-41-generic
}